Desmond Lamont Bishop
American NFL football player
Desmond J. Bryant
American NFL football player
Desmond Child (born John Charles Barret) American songwriter
Desmond Dekker (born Desmond Adolphus Dacres)
Jamaican musician
Desmond Harrington
American actor
Desmond Leo Haynes
Barbadian cricketer
Desmond Kevin Howard
American NFL football player
Desmond Llewelyn
Welsh actor
Desmond "Des" McAnuff
American theater director
Desmond John Morris
English zoologist and author
Desmond Bernard "Des" O'Connor
English comedian and singer
Desmond Mpilo Tutu
South African bishop and activist
Desmond Thomas Doss
American WWII Medal of Honor recipient; subject of film "Hacksaw Ridge"