(Alfred) Duff Cooper
1st Viscount Norwich, British former Secretary of War
Duff Clark "Duffy" Jackson
American jazz drummer
Jeffrey Adam "Duff" Goldman
American baker and Food Network host, star of TV's "Ace of Cakes"
Michael Andrew "Duff" McKagan
bassist of American band Guns N' Roses
Duff Badgley
American politician and journalist; father of actor Penn Badgley
Duff Haffenreffer
son of American TV journalist Lara Spencer