General Shepherd
main antagonist in "Call of Duty: Modern Warfare 2"
Dr. Derek Shepherd
a main character in the TV show "Grey's Anatomy"
Dr. Amelia Shepherd
a main character in the TV show "Grey's Anatomy"
Derrial Book (called Shepherd Book)
pastor in "Firefly" and its sequel movie, "Serenity"
Jon Shepherd
character on "Stargate Atlantis"
Jason Shepherd
character in "Big Fat Liar"
shepherd's pie
or cottage pie, a meat pie with a crust of mashed potatoes
Gwyneth Shepherd
main protagonist in Kerstin Gier's "Ruby Red Trilogy"
John/Jane Shepherd
the default names of the player decided gender main character of the popular sci,fi game series "Mass Effect"